Definition of «small molecule inhibitors»

Small molecule inhibitors refer to a class of compounds that can bind to specific target proteins, such as enzymes or receptors, and block their activity. These small molecules work by interfering with the normal function of these proteins, often by occupying the same binding site where an endogenous substrate would normally bind. By doing so, they can modulate cellular processes, inhibit the growth of cancer cells or prevent the replication of viruses. Small molecule inhibitors are widely used as drugs and have become increasingly important in drug discovery due to their ability to target specific proteins with high precision.

Sentences with «small molecule inhibitors»

An ideal model for the evaluation of small molecule inhibitors in two disease models simultaneously. (biomedcode.com)
Those features present significant challenges in drug discovery, and in fact, DNA - binding proteins traditionally have been considered to be beyond the reach of even small molecule inhibitors. (sciencedaily.com)
Unfortunately, not every gene product can be targeted with conventional small molecule inhibitors. (senginemedicine.com)
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